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Men's March Madness 2025: Sunday betting odds, lines, totals and BPI

Johni Broome and the Auburn Tigers secured the No. 1 overall seed in the 2025 men's NCAA tournament. Photo by Stew Milne/Getty Images

The 2025 men's NCAA tournament began with 68 teams looking to raise a banner and write their name into college basketball history. The Auburn Tigers, the overall No. 1 seed in the South, are looking to avenge their SEC tournament loss and claim the title as the best team in the country.

The SEC made a big statement in sending 14 teams to the Big Dance but faces stark competition from a formidable Houston team and the return of a healthy Cooper Flagg to the Duke Blue Devils.

Here are the lines, spreads and totals from Sunday's second-round matchups.

Odds are accurate as of publication time. All times Eastern. For the latest odds, go to ESPN BET.

Sunday - Round 2

(8) UConn Huskies
(1) Florida Gators -9.5

Men's Basketball Championship - West Region, 12:10 p.m. Lenovo Center, Raleigh, NC


Uconn: 23-10, 14-6 in Big East play
Florida: 29-4, 14-4 in SEC play

Odds by ESPN BET Moneyline: Florida (-600), Uconn (+400) Total: 150.5

BPI Projection: Florida by 3.8, straight up: 64.7%


(9) Baylor Bears
(1) Duke Blue Devils -12.5

Men's Basketball Championship - East Region, 2:40 p.m. Lenovo Center, Raleigh, NC


Baylor: 19-14, 10-10 in Big 12 play
Duke: 31-3, 19-1 in ACC play

Odds by ESPN BET Moneyline: Duke (-1200), Baylor (+700) Total: 144.5

BPI Projection: Duke by 9.4, straight up: 81.8%


(6) Illinois Fighting Illini -2.5
(3) Kentucky Wildcats

Men's Basketball Championship - Midwest Region, 5:15 p.m. Fiserv Forum, Milwaukee, WI


Illinois: 21-12, 12-8 in Big Ten play
Kentucky: 22-11, 10-8 in SEC play

Odds by ESPN BET Moneyline: Illinois (-135), Kentucky (+115) Total: 169.5

BPI Projection: Kentucky by 0.7, straight up: 52.6%


(7) Saint Mary's Gaels
(2) Alabama Crimson Tide -5.5

Men's Basketball Championship - East Region, 6:10 p.m. Rocket Arena, Cleveland, OH


Saint Mary's: 28-5, 17-1 in WCC play
Alabama: 25-8, 13-5 in SEC play

Odds by ESPN BET Moneyline: Alabama (-240), Saint Mary's (+200) Total: 149.5

BPI Projection: Alabama by 5.2, straight up: 69.7%


(12) Colorado State Rams
(4) Maryland Terrapins -7.5

Men's Basketball Championship - West Region, 7:10 p.m. Climate Pledge Arena, Seattle, WA


Colorado State: 25-9, 16-4 in MW play
Maryland: 25-8, 14-6 in Big Ten play

Odds by ESPN BET Moneyline: Maryland (-380), Colorado State (+290) Total: 143.5

BPI Projection: Maryland by 7, straight up: 75.3%


(6) Ole Miss Rebels
(3) Iowa State Cyclones -5.5

Men's Basketball Championship - South Region, 7:45 p.m. Fiserv Forum, Milwaukee, WI


Ole Miss: 22-11, 10-8 in SEC play
Iowa State: 24-9, 13-7 in Big 12 play

Odds by ESPN BET Moneyline: Iowa State (-230), Ole Miss (+195) Total: 145.5

BPI Projection: Iowa State by 5.5, straight up: 70.7%


(10) New Mexico Lobos
(2) Michigan State Spartans -7.5

Men's Basketball Championship - South Region, 8:40 p.m. Rocket Arena, Cleveland, OH


New Mexico: 26-7, 17-3 in MW play
Michigan State: 27-6, 17-3 in Big Ten play

Odds by ESPN BET Moneyline: Michigan State (-320), New Mexico (+260) Total: 148.5

BPI Projection: Michigan State by 6.8, straight up: 74.7%


(5) Oregon Ducks
(4) Arizona Wildcats -3.5

Men's Basketball Championship - East Region, 9:40 p.m. Climate Pledge Arena, Seattle, WA


Oregon: 24-9, 12-8 in Big Ten play
Arizona: 22-12, 14-6 in Big 12 play

Odds by ESPN BET Moneyline: Arizona (-170), Oregon (+145) Total: 152.5

BPI Projection: Arizona by 4.9, straight up: 68.7%