Who should you start? Who should you sit? To help you set your fantasy football lineups and to avoid starting a player who won't be in the lineup, we'll post fantasy-relevant updates and analysis here as NFL teams release their inactives, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
Sunday night game
Sammy Watkins, WR, KC: Hamstring -- OUT
Impact: Mecole Hardman has been activated from the reserve/COVID-19 list. Demarcus Robinson/Byron Pringle could end up playing on 3-WR sets.
Jalen Richard, RB, LV: Chest -- OUT
4 p.m. ET games
Offense
Drew Lock, QB, DEN: Ribs -- Active
Impact: Practiced all week, so was fully expected to start, even at less than 100%.
Noah Fant, TE, DEN: Ribs -- Active
Impact: Also practiced enough during the week that a start was to be expected.
Allen Lazard, WR, GB: Abdomen -- Active
Impact: Malik Taylor could be in the mix if he can't finish the game.
Darrius Shepherd, WR, GB: Shoulder -- Active
Impact: Equanimeous St. Brown might not get another chance to showcase his skills.
Jack Doyle, TE, IND: Concussion -- Active
Impact: Even so, Mo Alie-Cox will likely be the best TE option for fantasy purposes in Indianapolis.
Tyrod Taylor, QB, LAC: Ribs -- Active
Impact: Not that there's any QB controversy here, as Justin Herbert has played very well. Still, it's worth noting that Taylor has finally been given a clean bill of health.
Irv Smith Jr., TE, MIN: Groin -- Active
Impact: Kyle Rudolph had just five targets with Smith out last week.
Sam Darnold, QB, NYJ: Shoulder -- Inactive
Impact: Joe Flacco will continue to start for the Jets.
Sam Ficken, K, NYJ: Groin -- Active
Impact: Sergio Castillo has missed just one of 11 kicks while filling in, but he's the one who sits this week.
Defense
DeMarcus Lawrence, DE, DAL: Illness -- Active
DeShawn Williams, DT, DEN: Ankle -- Active
Bryce Callahan, CB, DEN: Illness -- Active
Kemoko Turay, DE, IND: Ankle -- Active
Kyle Van Noy, LB, MIA: Hip -- Active
Cameron Dantzler, CB, MIN: Concussion -- Active
Blake Cashman, LB, NYJ: Hamstring -- Inactive
Bless Austin, CB, NYJ: Neck -- OUT/IR
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games and 2:30 p.m. ET for the late games.
1 p.m. ET games
Offense
Teddy Bridgewater, QB, CAR: Knee -- Inactive
Impact: It's P.J. Walker who will start at quarterback and take all the snaps.
Christian McCaffrey, RB, CAR: Shoulder -- OUT
Impact: Mike Davis' run as the Panthers' No. 1 RB continues for at least one more week.
Joe Mixon, RB, CIN: Foot -- OUT/IR
Impact: May well miss the remainder of the season. Giovani Bernard to take over the Bengals' backfield.
Matthew Stafford, QB, DET: Thumb -- Active
Impact: Was always expected to start, but as you can see below, his offensive options will be limited.
D'Andre Swift, RB, DET: Concussion -- OUT
Impact: Adrian Peterson and Kerryon Johnson will split carries.
Danny Amendola, WR, DET: Hip -- OUT
Impact: Marvin Jones Jr. will handle the Lions' No. 1 WR duties ...
Kenny Golladay, WR, DET: Hip -- OUT
Impact: ... with Marvin Hall stepping in as the No. 2. Mohamed Sanu Sr. also in the mix.
Kenny Stills, WR, HOU: Back -- Active
Impact: More targets may arise for Keke Coutee/Isaiah Coulter if Stills can't play a full 60 minutes.
Gardner Minshew II, QB, JAX: Thumb -- Inactive
Impact: Still a weekly question mark. Jake Luton has done well in his stead.
Laviska Shenault Jr., WR, JAX: Hamstring -- OUT
Impact: Keelan Cole Sr. should once again take over Shenault's workload.
James O'Shaughnessy, TE, JAX: Knee -- OUT
Impact: Tyler Eifert gets all of what should be a tiny amount of TE targets.
Damien Harris, RB, NE: Ankle -- Active
Impact: Sony Michel is off the IR, but inactive, saving Harris from being in a true committee.
N'Keal Harry, WR, NE: Shoulder -- Active
Impact: Jakobi Meyers is the only other fantasy-viable WR option on the team.
Ryan Izzo, TE, NE: Hamstring -- Active
Impact: Jordan Thomas is also around as a backup option.
Nick Folk, K, NE: Back -- Active
Impact: It would have been a surprise if he hadn't been out there when kickoff came around.
Josh Hill, TE, NO: Concussion -- OUT
Impact: Jared Cook will handle TE duties, with Taysom Hill likely to step in for injured QB Drew Brees.
Adam Humphries, WR, TEN: Concussion -- OUT
Impact: Kalif Raymond/Cameron Batson could see a few extra targets.
Dontrelle Inman, WR, WSH: Hamstring -- Inactive
Impact: Steven Sims Jr. should see his fantasy value with Inman sitting ...
Isaiah Wright, WR, WSH: Illness -- Active
Impact: ... with the same being true for Cam Sims, even as Wright suits up.
Dustin Hopkins, K, WSH: Groin -- Active
Impact: Kaare Vedvik stays on the practice squad, so Hopkins should play.
Defense
Calais Campbell, DE, BAL: Calf -- Inactive
Brandon Williams, DT, BAL: Ankle -- Inactive
Yetur Gross-Matos, DE, CAR: Shoulder -- Active
Tahir Whitehead, LB, CAR: Ribs -- Active
Donte Jackson, CB, CAR: Toe -- Inactive
Rasul Douglas, CB, CAR: Ankle -- Active
Mack Wilson, LB, CLE: Hip -- Active
Da'Shawn Hand, DE, DET: Groin -- Inactive
Jarrad Davis, LB, DET: Knee -- Active
Lawrence Guy, DT, NE: Shoulder -- Active
John Simon, DE, NE: Elbow -- Active
Deatrich Wise Jr., DE, NE: Knee -- Active
Adam Butler, DT, NE: Shoulder -- Inactive
Ja'Whaun Bentley, LB, NE: Groin -- Active
Stephon Gilmore, CB, NE: Knee -- Active
Marshon Lattimore, CB, NO: Abdomen -- Inactive
Jadeveon Clowney, DE, TEN: Knee -- OUT/IR
Adoree' Jackson, CB, TEN: Knee -- OUT
Kenny Vaccaro, S, TEN: Concussion -- OUT
Deshazor Everett, S, WSH: Ankle -- OUT