Ligue 1 leaders Monaco will face a trip to Marseille in the Coupe de France round of 16.
Thursday's draw, for matches to be played on Feb. 28 and March 1, also gave Paris Saint-Germain a match away from home at Ligue 2's Niort.
The only other fixture between top-flight sides sees Bordeaux at home against Lorient.
The two fourth-tier teams still playing will also be at home, with Bergerac Perigord facing Lille, and Frejus hosting Auxerre.
Coupe de France round of 16 draw: