Everton's Yerry Mina is still recovering from a foot injury and will miss Saturday's Premier League visit of Southampton, according to manager Marco Silva.
Mina, 23, joined Everton from Barcelona on transfer deadline day and missed the Merseyside club's 2-2 draw with Wolverhampton Wanderers on the opening weekend of the new season.
"I can tell you Mina is not available for the match. He is recovering from a small problem in his foot," Silva told a news conference.
Fellow new signing Richarlison, who struck twice against Wolves before going off with a cramp, has been cleared to play in the game at Goodison Park.
Midfielder Andre Gomes will not feature as he battles to shake off a hamstring injury while defender Kurt Zouma and playmaker Bernard are available to make their debuts.
"We've made new signings and I want there to be competition for each position. As a squad, it is the way I like to work. I like to have problems when making my decisions," Silva added.
Southampton began their campaign with a goalless draw against Burnley.