Juventus defender Gleison Bremer will undergo surgery after sustaining an anterior cruciate ligament injury in their Champions League game at RB Leipzig, the club said on Thursday.
The 27-year-old Brazil international was forced off six minutes into Juve's 3-2 win over Leipzig on Wednesday and was replaced by Federico Gatti.
Juventus were dealt another blow with midfielder Nico Gonzalez suffering a thigh muscle injury.
"Gleison Bremer and Nico Gonzalez underwent diagnostic tests ... which revealed an anterior cruciate ligament injury in the left knee for the former and a low-grade injury to the rectus femoris of the right thigh for the latter," the club said in a statement.
"Bremer will undergo surgery in the coming days."
Bremer, who joined Juve in 2022, has been a key defender for the Italians having so far played every minute of the Serie A campaign in which they have not conceded in their six matches.
The 27-year-old has been replaced by Paris Saint-Germain's Lucas Berlado for month's World Cup qualifiers against Chile and Peru, the Brazilian FA (CBF) said on Thursday.
Beraldo, 20, was a regular starter for Sao Paulo before PSG signed him on a five-year contract in January. He made his debut for Brazil in March.