Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of LaLiga fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire and subject to updates.)
Athletic Club v Villarreal
San Mamés, Bilbao
Sunday, 3:15 p.m. GMT / 10:15 a.m. ET
Latest Athletic Club team news
Expected Lineup:
GK Unai Núñez
LB Yuri Berchiche | CB Yeray | CB Dani Vivian | RB Óscar de Marcos
DM Beñat Prados | DM Iñigo Ruiz de Galarreta
LW Nico Williams | AM Oihan Sancet | RW Iñaki Williams
ST Gorka Guruzeta
Injury/suspension updates:
Ander Herrera, M, hamstring, OUT, estimated return Dec. 21
Latest Villarreal team news
Expected Lineup:
GK Diego Conde
LB Juan Bernat | CB Raúl Albiol | CB Logan Costa | RB
LM Álex Baena | CM Santi Comesaña | CM Dani Parejo | RM Yeremy Pino
ST Thierno Barry | ST Gerard Moreno
Injury/suspension updates:
Ilias Akhomach, F, knee, OUT, estimated return Jul. 1
Eric Bailly, D, shoulder, OUT, estimated return Dec. 15
Sergi Cardona, D, suspension, due back Dec. 15
Juan Foyth, D, knee, OUT, estimated return Dec. 15
Alfonso Pedraza, D, ankle, OUT, estimated return Dec. 15
Nicolas Pépé, F/M, thigh, OUT, estimated return Dec. 22
Ayoze Pérez, F/M, thigh, OUT, estimated return Dec. 15
Ramón Terrats, M, achilles, OUT, estimated return Dec. 15
Osasuna v Alavés
El Sadar, Pamplona
Sunday, 5:30 p.m. GMT / 12:30 p.m. ET
Latest Osasuna team news
Expected Lineup:
GK Sergio Herrera
LB Juan Cruz | CB Flavien-Enzo Boyomo | CB Alejandro Catena | RB Jesús Areso
CM Iker Muñoz | CM Jon Moncayola | CM Aimar Oroz
FWL Rubén Peña | ST Ante Budimir | FWR Rubén García
Injury/suspension updates:
José Arnaiz, F, hamstring, DOUBT
Lucas Torró, M, suspension, due back Dec. 8
Bryan Zaragoza, M, foot, OUT, estimated return Jan. 11
Latest Alavés team news
Expected Lineup:
GK Antonio Sivera
LB Manu Sánchez | CB Abdel Abqar | CB Santiago Mouriño | RB Nahuel Tenaglia
CM Antonio Blanco | CM Ander Guevara | CM Jon Guridi
FWL Carlos Martín | ST Enrique García | FWR Carlos Vicente
Injury/suspension updates:
Moussa Diarra, D, illness, OUT, estimated return Dec. 15
Hugo Novoa, M, abdomen, DOUBT
Carlos Benavídez, M, hamstring, DOUBT
Atlético Madrid v Sevilla
Riyadh Air Metropolitano, Madrid
Sunday, 8 p.m. GMT / 3 p.m. ET
Latest Atlético Madrid team news
Expected Lineup:
GK Jan Oblak
LB Javi Galán | CB José María Giménez | CB Clément Lenglet | RB Marcos Llorente
LM Conor Gallagher | CM Pablo Barrios | CM Rodrigo De Paul | RM Giuliano Simeone
ST Julián Álvarez | ST Antoine Griezmann
Injury/suspension updates:
Thomas Lemar, M, undisclosed, OUT, estimated return Dec. 15
Nahuel Molina, M/D, thigh, DOUBT
Latest Sevilla team news
Expected Lineup:
GK Álvaro Fernández
LB Adrià Pedrosa | CB Loïc Badé | CB Enrique Salas | RB José Ángel Carmona
DM Albert Sambi Lokonga | DM Nemanja Gudelj
LW Peque | AM Djibril Sow | RW Dodi Lukebakio
ST Isaac Romero
Injury/suspension updates:
Chidera Ejuke, F, hamstring, DOUBT
Tanguy Nianzou, D, thigh, OUT, estimated return Dec. 22
Ørjan Nyland, G, knee, DOUBT
Getafe v Espanyol
Estadio Coliseum, Getafe
Monday, 8 p.m. GMT / 3 p.m. ET
Latest Getafe team news
Expected Lineup:
GK David Soria
LB Diego Rico | CB Omar Alderete | CB Djené | RB Allan Nyom
LM Álex Sola | CM Mauro Arambarri | CM Luis Milla | RM Carles Pérez
ST Bertug Yildirim | ST Christantus Uche
Injury/suspension updates:
Carles Aleñá, M, undisclosed, DOUBT
Borja Mayoral, F, strain, DOUBT
Latest Espanyol team news
Expected Lineup:
GK Joan García
LB Brian Oliván | CB Leandro Cabrera | CB Sergi Gómez | RB Omar El Hilali
DM Pol Lozano
LM Javier Puado | CM Alex Král | CM Justin Smith | RM Jofre Carreras
ST Irvin Cardona
Injury/suspension updates:
Fernando Calero, D, achilles, OUT, estimated return Dec. 14
Edu Expósito, M, knee, OUT, estimated return Dec. 14
José Gragera, M, illness, OUT, estimated return Dec. 14
Marash Kumbulla, D, suspension, due back Dec. 14