Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of LaLiga fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire and subject to updates.)
Espanyol v Real Valladolid
RCDE Stadium, Barcelona
Friday, 8 p.m. GMT / 3 p.m. ET
Latest Espanyol team news
Expected Lineup:
GK Joan García
LB Brian Oliván | CB Leandro Cabrera | CB Marash Kumbulla | RB Omar El Hilali
DM Pol Lozano
LM Jofre Carreras | CM Álvaro Tejero | CM Alex Král | RM Antoniu Roca
ST Javier Puado
Injury/suspension updates:
José Gragera, M, illness, OUT, estimated return Jan. 25
Carlos Romero, D, strain, DOUBT
Latest Real Valladolid team news
Expected Lineup:
GK Karl Hein
LB Lucas Rosa | CB Juma Bah | CB Javi Sánchez | RB Luis Pérez
CM Stanko Juric | CM Mario Martín | CM Enrique Perez
FWL Raúl Moro | ST Marcos André | FWR Anuar
Injury/suspension updates:
Eray Cömert, M/D, hamstring, OUT, estimated return Feb. 23
Enrique Perez, M, undisclosed, DOUBT
Mamadou Diallo, F, undisclosed, OUT, estimated return Jan. 26
Anuar, F/M, undisclosed, DOUBT
Girona v Sevilla
Municipal de Montilivi, Girona
Saturday, 1 p.m. GMT / 8 a.m. ET
Latest Girona team news
Expected Lineup:
GK Paulo Gazzaniga
LB Daley Blind | CB Ladislav Krejcí | CB David López | RB Arnau Martínez
CM Iván Martín | CM Oriol Romeu
LW Miguel Gutiérrez | AM Donny van de Beek | RW Bryan Gil
ST Abel Ruiz
Injury/suspension updates:
Yáser Asprilla, M, ankle, DOUBT
Miguel Gutiérrez, M/D, undisclosed, DOUBT
Yangel Herrera, M, suspension, due back Jan. 26
Portu, F/M, ankle, DOUBT
Bojan Miovski, F, sprain, OUT, estimated return Jan. 26
Latest Sevilla team news
Expected Lineup:
GK Ørjan Nyland
LB Adrià Pedrosa | CB Loïc Badé | CB Nemanja Gudelj | RB José Ángel Carmona
DM Albert Sambi Lokonga
CM Saúl Ñíguez | CM Djibril Sow
LW Ruben Vargas | RW Dodi Lukebakio
ST Isaac Romero
Injury/suspension updates:
Valentín Barco, D, groin, DOUBT
Chidera Ejuke, F, hamstring, DOUBT
Kelechi Iheanacho, F, strain, DOUBT
Tanguy Nianzou, D, thigh, OUT, estimated return Jan. 25
Leganés v Atlético Madrid
Butarque, Leganés, Madrid
Saturday, 3:15 p.m. GMT / 10:15 a.m. ET
Latest Leganés team news
Expected Lineup:
GK Marko Dmitrovic
LB Javi Hernández | CB Sergio González | CB Matija Nastasic | CB Renato Tapia
CM Darko Brasanac | CM Seydouba Cissé | CM Yvan Neyou
ST Miguel De la Fuente | ST Raba
Injury/suspension updates:
Julián Chicco, M, undisclosed, DOUBT
Enric Franquesa, D, knee, OUT, estimated return Sep. 1
Raba, F, undisclosed, DOUBT
Óscar Rodríguez, F/M, suspension, due back Jan. 26
Juan Soriano, G, suspension, due back Jan. 26
Latest Atlético Madrid team news
Expected Lineup:
GK Jan Oblak
LB Javi Galán | CB Robin Le Normand | CB Clément Lenglet | RB Nahuel Molina
LM Conor Gallagher | CM Pablo Barrios | CM Rodrigo De Paul | RM Giuliano Simeone
ST Julián Álvarez | ST Antoine Griezmann
Injury/suspension updates:
José María Giménez, D, strain, DOUBT
Alexander Sorloth, F, undisclosed, OUT, estimated return Jan. 21
Real Betis v Alavés
Benito Villamarín, Sevilla
Saturday, 5:30 p.m. GMT / 12:30 p.m. ET
Latest Real Betis team news
Expected Lineup:
GK Francisco Barbosa Vieites
LB Romain Perraud | CB Marc Bartra | CB Diego Llorente | RB Youssouf Sabaly
DM Sergi Altimira | DM Johnny Cardoso
LW Abde Ezzalzouli | AM Isco | RW Pablo Fornals
ST Vitor Roque
Injury/suspension updates:
Chimy Ávila, F, knee, DOUBT
Héctor Bellerín, D, foot, DOUBT
William Carvalho, M, achilles, OUT, estimated return May. 4
Pablo Fornals, F/M, undisclosed, DOUBT
Giovani Lo Celso, F/M, groin, OUT, estimated return Feb. 2
Marc Roca, M, ankle, DOUBT
Aitor Ruibal, D, ankle, OUT, estimated return Jan. 25
Latest Alavés team news
Expected Lineup:
GK Jesus Owono
LB Manu Sánchez | CB Abdel Abqar | CB Moussa Diarra | RB Nahuel Tenaglia
LM Carlos Martín | CM Antonio Blanco | CM Jon Guridi | CM Joan Jordán | RM Carlos Vicente
ST Enrique García
Injury/suspension updates:
Joan Jordán, M, undisclosed, DOUBT
Carlos Martín, F, undisclosed, DOUBT
Santiago Mouriño, D, undisclosed, DOUBT
Luka Romero, F/M, undisclosed, DOUBT
Antonio Sivera, G, hand, OUT, estimated return Feb. 16
Getafe v Barcelona
Estadio Coliseum, Getafe
Saturday, 8 p.m. GMT / 3 p.m. ET
Latest Getafe team news
Expected Lineup:
GK David Soria
LB Diego Rico | CB Omar Alderete | CB Domingos Duarte | CB Djené | RB Juan Iglesias
CM Mauro Arambarri | CM Luis Milla
AM Coba da Costa | AM Christantus Uche
ST Borja Mayoral
Injury/suspension updates:
Allan Nyom, M/D, undisclosed, DOUBT
Jesus Santiago Perez, M, illness, DOUBT
Latest Barcelona team news
Expected Lineup:
GK Iñaki Peña
LB Alejandro Balde | CB Ronald Araújo | CB Pau Cubarsí | RB Jules Koundé
DM Marc Casadó | DM Pedri
LW Raphinha | AM Dani Olmo | RW Lamine Yamal
ST Robert Lewandowski
Injury/suspension updates:
Marc Bernal, M/D, knee, OUT, estimated return Sep. 1
Andreas Christensen, D, achilles, DOUBT
Iñigo Martínez, D, hamstring, OUT, estimated return Feb. 16
Marc-André ter Stegen, G, knee, OUT, estimated return Apr. 6
Ferran Torres, F, calf, DOUBT
Celta Vigo v Athletic Club
Estadio Abanca-Balaídos, Vigo
Sunday, 1 p.m. GMT / 8 a.m. ET
Latest Celta Vigo team news
Expected Lineup:
GK Vicente Guaita
LB Óscar Mingueza | CB Carlos Dominguez Caceres | CB Javi Rodríguez | CB Carl Starfelt
DM Fran Beltrán | DM Ilaix Moriba
AM Pablo Durán | AM Jonathan Bamba
ST Borja Iglesias
Injury/suspension updates:
Marcos Alonso, M/D, suspension, due back Jan. 27
Iago Aspas, F, calf, OUT, estimated return Feb. 9
Fer Lopez, F/M, ankle, DOUBT
Jailson, M, groin, DOUBT
Mihailo Ristic, D, thigh, DOUBT
Latest Athletic Club team news
Expected Lineup:
GK Unai Simón
LB Yuri Berchiche | CB Aitor Paredes | CB Dani Vivian | RB Óscar de Marcos
DM Mikel Jauregizar | DM Beñat Prados
LW Nico Williams | AM Oihan Sancet | RW Iñaki Williams
ST Gorka Guruzeta
Injury/suspension updates:
Oihan Sancet, F/M, ankle, DOUBT
Real Madrid v Las Palmas
Santiago Bernabéu, Madrid
Sunday, 3:15 p.m. GMT / 10:15 a.m. ET
Latest Real Madrid team news
Expected Lineup:
GK Thibaut Courtois
LB Ferland Mendy | CB Raúl Asencio | CB Antonio Rüdiger | RB Lucas Vázquez
DM Aurélien Tchouaméni
CM Jude Bellingham | CM Federico Valverde
FWL Brahim Díaz | ST Kylian Mbappé | FWR Rodrygo
Injury/suspension updates:
David Alaba, D, knee, DOUBT
Eduardo Camavinga, M, hamstring, DOUBT
Dani Carvajal, D, knee, OUT, estimated return Aug. 1
Vinícius Jr., F, suspension, due back Feb. 2
Éder Militão, D, knee, OUT, estimated return Aug. 1
Luka Modric, M, suspension, due back Jan. 25
Aurélien Tchouaméni, M, concussion, DOUBT
Latest Las Palmas team news
Expected Lineup:
GK Jasper Cillessen
LB Mika Mármol | CB Scott McKenna | CB Álex Suárez | RB Juan Herzog
DM Enzo Loiodice | DM Kirian Rodríguez
LW Alberto Moleiro | AM Javier Munoz | RW Sandro
ST Fábio Silva
Injury/suspension updates:
Marvin, M/D, undisclosed, DOUBT
José Campaña, M, undisclosed, DOUBT
Dário Essugo, M, suspension, due back Jan. 24
Viti, M/D, knee, DOUBT
Osasuna v Rayo Vallecano
El Sadar, Pamplona
Sunday, 5:30 p.m. GMT / 12:30 p.m. ET
Latest Osasuna team news
Expected Lineup:
GK Aitor Fernández
LB Juan Cruz | CB Flavien-Enzo Boyomo | CB Alejandro Catena | RB Jesús Areso
CM Jon Moncayola | CM Aimar Oroz | CM Lucas Torró
FWL Enrique Barja | ST Ante Budimir | FWR Rubén García
Injury/suspension updates:
José Arnaiz, F, illness, DOUBT
Sergio Herrera, G, concussion, DOUBT
Rubén Peña, M/D, illness, DOUBT
Bryan Zaragoza, M, foot, DOUBT
Latest Rayo Vallecano team news
Expected Lineup:
GK Daniel Cardenas
LB Pep Chavarría | CB Florian Lejeune | CB Abdul Mumin | RB Andrei Ratiu
DM Unai López | DM Óscar Valentín
LW Álvaro García | AM Isi Palazón | RW Jorge de Frutos
ST Sergio Camello
Injury/suspension updates:
Pathé Ciss, M, suspension, due back Jan. 26
Raul de Tomas, F, illness, OUT, estimated return Jan. 26
Valencia v Real Sociedad
Mestalla, Valencia
Sunday, 8 p.m. GMT / 3 p.m. ET
Latest Valencia team news
Expected Lineup:
GK Giorgi Mamardashvili
LB José Gayà | CB Cristhian Mosquera | CB César Tárrega | RB Dimitri Foulquier
DM Enzo Barrenechea | DM Javi Guerra
LW Diego López | AM Andre Almeida | RW Luis Rioja
ST Hugo Duro
Injury/suspension updates:
Thierry Correia, D, knee, OUT, estimated return Jul. 1
Mouctar Diakhaby, D, knee, OUT, estimated return Jan. 26
José Gayà, D, foot, DOUBT
Rafa Mir, F, quadriceps, DOUBT
Francisco Perez, M, hamstring, DOUBT
Latest Real Sociedad team news
Expected Lineup:
GK Álex Remiro
LB Aihen Muñoz | CB Nayef Aguerd | CB Jon Pacheco | RB Jon Aramburu
DM Beñat Turrientes
LM Ander Barrenetxea | CM Brais Méndez | CM Luka Sucic | RM Sergio Gómez
ST Mikel Oyarzabal
Injury/suspension updates:
Álvaro Odriozola, D, undisclosed, OUT, estimated return Jan. 19
Hamari Traoré, D, knee, OUT, estimated return May. 4
Igor Zubeldia, D, suspension, due back Jan. 19
Villarreal v Mallorca
Estadio de la Cerámica, Villarreal
Monday, 8 p.m. GMT / 3 p.m. ET
Latest Villarreal team news
Expected Lineup:
GK Luiz Junior
LB Sergi Cardona | CB Raúl Albiol | CB Logan Costa | RB
LM Denis Suárez | CM Pape Gueye | CM Dani Parejo | RM Gerard Moreno
ST Thierno Barry | ST Álex Baena
Injury/suspension updates:
Ilias Akhomach, F, knee, OUT, estimated return Jul. 1
Diego Conde, G, knee, DOUBT
Alfonso Pedraza, D, ankle, DOUBT
Nicolas Pépé, F/M, thigh, DOUBT
Ayoze Pérez, F/M, thigh, DOUBT
Yeremy Pino, F/M, suspension, due back Jan. 20
Ramón Terrats, M, achilles, OUT, estimated return Jan. 20
Latest Mallorca team news
Expected Lineup:
GK Dominik Greif
LB Johan Mojica | CB Antonio Raíllo | CB Martin Valjent | RB Pablo Maffeo
DM Samú Costa | DM Omar Mascarell
LW Cyle Larin | AM Sergi Darder | RW Dani Rodríguez
ST Vedat Muriqi
Injury/suspension updates:
Samú Costa, M, calf, DOUBT
Iván Cuéllar, G, suspension, due back Feb. 1
Manu Morlanes, M, knee, OUT, estimated return Sep. 1
Antonio Raíllo, D, undisclosed, DOUBT