Coco Gauff proved too strong for former finalist Madison Keys in their all-American third-round duel at the US Open, racing to a 6-2, 6-3 win in just over an hour at Arthur Ashe Stadium in New York on Friday.
The 12th-seeded Gauff will next take on China's Shuai Zhang, who advanced with a 6-2, 6-4 victory over Rebecca Marino.
At age 18, Gauff is the youngest American woman to have made the round of 16 at all four majors since 18-year-old Venus Williams, who accomplished the feat in 1998, according to ESPN Stats & Information.
In another match, No. 5 seed Ons Jabeur finally made it through to the fourth round, defeating No. 31 Shelby Rogers 4-6, 6-4, 6-3.
Jabeur had been stopped in the third round in each of her past three trips to Flushing Meadows before overcoming Rogers in 2 hours, 17 minutes.
"Finally," the Wimbledon runner-up from Tunisia said with a smile. "I know that I don't play the best on hard courts, but it's always amazing to see how I'm improving, how I'm pushing my limits."
Next up for Jabeur is No. 18 Veronika Kudermetova, who needed only 47 minutes to sweep past Dalma Galfi 6-2, 6-0.
Caroline Garcia knocked out 2019 champion Bianca Andreescu, as the No. 17 seed from France continued her strong summer surge with a 6-3, 6-2 victory that moved her into the fourth round. Garcia has won 11 straight matches, including the title last month in Cincinnati. She was ranked as low as No. 79 earlier in the summer.
Top-ranked Iga Swiatek is the only other top-five woman still in the tournament. No. 3 Maria Sakkari and No. 4 Paula Badosa were eliminated with three-set losses.
The Associated Press and Reuters contributed to this report.