Jaguars (1-7) at Packers (6-2)
1 p.m. ET | Fox
Matchup rating: 47.1 | Spread: GB -14 (52)
What to watch for: The Packers don't lose to teams like this often. They're 14-3 in games against teams with a winning percentage of .125 or worse with Aaron Rodgers as their quarterback, according to ESPN Stats & Information research. And Rodgers is 15-2 in his career as at least a 12-point favorite. The only two losses came in 2018 to the Arizona Cardinals as a 13.5-point favorite and in 2011 at the Kansas City Chiefs as a 13-point favorite. -- Rob Demovsky
Bold prediction: Jacksonville QB Jake Luton will be sacked at least four times on Sunday. The Packers don't blitz a lot; they rank 25th in that area. But is there a better time to break tendencies than when facing a rookie QB making just his second start? Luton completed just 4 of 13 passes and threw an interception when he was under pressure in his debut against the Houston Texans, and while the Packers have blitzed 69 times this season, they have picked up five of their 17 sacks when doing so. -- Mike DiRocco
Stat to know: Per the Elias Sports Bureau, Green Bay wide receiver Davante Adams joined Calvin Johnson (2012) as the only players in NFL history with three games of at least 10 receptions, 150 receiving yards and a receiving TD in a season -- and Adams has only played six games this year.
What to know for fantasy: Jaguars running back James Robinson has six games with more than 14.5 fantasy points this season. The only running backs with more such games this season are a pair of guys you've likely heard of: Alvin Kamara (8) and Dalvin Cook (7). See Week 10 rankings.
Betting nugget: Jacksonville is 1-5 against the spread in games that follow a loss this season. And Green Bay is 5-1 ATS against teams with losing records. Read more.
DiRocco's pick: Packers 31, Jaguars 17
Demovsky's pick: Packers 33, Jaguars 13
FPI prediction: GB, 90.7% (by an average of 17.7 points)
Matchup must-reads: Jags QB Luton to start again for injured Minshew ... Good luck, bad luck or another word for Packers' changing injury situation ... Jaguars find mild success blitzing, but next opponents handle it well ... Packers' Rodgers says NFL's virus policy has double standards